Bad backs run in the family, I throw mine out a few times a year and take ibuprofen for the pain. After a week or so I'm usually feeling fine and I stop taking ibuprofen. But when I was 18 years old, I worked in a wearhouse throwing freight all day, I used to take 2400 mg a day to keep the tendonitis in my wrists under control--but I haven't taken meds like this for almost 10 years. NSAIDs cause hypertension, that's a given. My blood pressure is sometimes a little on the high side, despite being in good shape, I'm 6'1" and 190 lbs. It's usually about 130/75, sometimes 135/80. Hypertension runs in my family, that's a factor. Will the heavy use of ibuprofen when I was 18-20 years old cause high blood pressure for the rest of my life? Is there a better anti-inflammatory substitute that's healthier when I have crippling back pain?